⚠️ Before you test: most people score 0, and that is the correct result

Unlike our Neanderthal Calculator (which finds a signal in nearly everyone of non-African descent), real Denisovan ancestry is essentially absent in Europeans, Africans, Middle Easterners, and most Latin Americans. It is substantial only in Melanesian, Papuan and Aboriginal Australian ancestry (several percent of the genome), and present at a smaller but real level in East/Southeast Asian, South Asian and Native American ancestry.

The score is an index, not a percentage of your genome: it is scaled so that the European reference average is 0 and the Papuan reference average is 100. A score around 0 means no Denisovan ancestry was detected, which is the expected outcome for the large majority of testers and not a sign that the tool failed.

✓ Denisovan marker panel ready, 147 diagnostic markers, 147 validated Denisovan-specific markers loaded

Drop your RAW DNA file here

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23andMeAncestryDNAMyHeritage FTDNALivingDNA.txt.gz.zip
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❓ How do I find my raw DNA file?

Methodology. Each of the 147 markers is an allele that the high-coverage Denisovan genome carries, that none of the three high-coverage Neanderthal genomes (Altai, Vindija, Chagyrskaya) carries, that is essentially absent in African populations, and that is clearly more common in Papuans than in Europeans. That last contrast is what makes the test specific: Europeans and Papuans share the same out-of-Africa history and the same Neanderthal ancestry, so what separates them at these positions is Denisovan ancestry. Reference genotypes come from the Allen Ancient DNA Resource (v66.p1, 1240K), and the scale is anchored on real reference populations. The panel was validated on individuals held out of its construction: Africans score about -9, Europeans about 2, Native Americans 31, East Asians 35-54, Melanesians 65, Aboriginal Australians 69 and Papuans 91-100.

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